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Review
. 2002 Feb;46(2):267-74.
doi: 10.1128/AAC.46.2.267-274.2002.

Evolution of drug resistance in Mycobacterium tuberculosis: clinical and molecular perspective

Stephen H Gillespie  1
Affiliations
Review

Evolution of drug resistance in Mycobacterium tuberculosis: clinical and molecular perspective

Stephen H Gillespie. Antimicrob Agents Chemother. 2002 Feb.
No abstract available

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Figures

FIG. 1.
FIG. 1.
Diagrammatic representation of the link between mutation rate, population size, and clinical complication in the emergence of resistance in M. tuberculosis infection. This demonstrates that individuals with tuberculosis in which the bacterial population increases or drug penetration is compromised by empyema or poor adherence are more likely to produce resistant mutants.
See this image and copyright information in PMC

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