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. 2002 Feb;46(2):517-8.
doi: 10.1128/AAC.46.2.517-518.2002.

In vitro activities of BMS-284756 against Chlamydia trachomatis and recent clinical isolates of Chlamydia pneumoniae

Sheila Malay  1 , Patricia M Roblin, Tamara Reznik, Andrei Kutlin, Margaret R Hammerschlag
Affiliations

In vitro activities of BMS-284756 against Chlamydia trachomatis and recent clinical isolates of Chlamydia pneumoniae

Sheila Malay et al. Antimicrob Agents Chemother. 2002 Feb.

Abstract

The in vitro activities of BMS-284756 (a novel des-fluoroquinolone), levofloxacin, moxifloxacin, and clarithromycin were tested against 5 strains of Chlamydia trachomatis and 20 isolates of Chlamydia pneumoniae. The MIC at which 90% of the isolates were inhibited and the minimal bactericidal concentration at which 90% of the isolates were killed by BMS-284756 for all isolates of C. pneumoniae and C. trachomatis was 0.015 microg/ml (range, 0.015 to 0.03 microg/ml). BMS-284756 was the most active quinolone tested.

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