Disseminated granulomatous meningoencephalomyelitis in a dog

Abstract

A 6-year-old, intact, female miniature Doberman pinscher was evaluated for lethargy, intermittent back pain, and unstable gait. Physical and neurological findings included bradycardia, hypothermia, hyperesthesia, progressive and ascending ataxia, and proprioceptive deficits in all limbs. Laboratory findings and magnetic resonance imaging were consistent with disseminated granulomatous meningoencephalomyelitis, confirmed later by microscopy.

Figure 1. Electrocardiogram at rest. Lead II rhythm strip, paper speed = 50 mm/s, 10 mm = 1 mV. Heart rate of 60 bpm and sinus arrest.

Figure 2. Electrocardiogram after 0.04 mg/kg bodyweight intravenous atropine. Lead II rhythm strip, paper speed = 50 mm/s, 10 mm = 1 mV. Heart rate increased to 90 bpm at a regular beat.