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. 2002 Jan;86(1):21-5.
doi: 10.1136/adc.86.1.21.

Efficacy of school urinary screening for membranoproliferative glomerulonephritis type 1

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Efficacy of school urinary screening for membranoproliferative glomerulonephritis type 1

Y Kawasaki et al. Arch Dis Child. 2002 Jan.

Abstract

Aims: In order to evaluate the efficacy of a school urinary screening programme, children with membranoproliferative glomerulonephritis (MPGN) type 1 were studied.

Methods: A total of 52 patients who had been diagnosed with MPGN type 1 from 1970 to 1997 were studied; 35 were identified after 1974 on screening (group S), and 17 were identified by presenting symptoms (group N), mostly before 1989.

Results: Mean blood pressure was 89 mm Hg in group S and 104 mm Hg in group N; urinary protein excretion was 0.9 g/day in group S and 3.0 g/day in group N. Histopathological evidence of chronic changes was found in six group S and 15 group N patients. No patients in group S had renal insufficiency, but five patients in group N required regular haemodialysis.

Conclusions: Results suggest that early identification by school urinary screening may enable early management and so improve prognosis of MPGN.

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Figures

Figure 1
Figure 1
The number of patients with MPGN type 1.
Figure 2
Figure 2
Renal survival rate.

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