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. 2002 Jan;65(1):65-8.
doi: 10.1021/np010327t.

A new triterpene saponin from Pittosporum viridiflorum from the Madagascar rainforest

Youngwan Seo  1 , John M Berger, Jeannine Hoch, Kim M Neddermann, Isia Bursuker, Steven W Mamber, David G I Kingston
Affiliations

A new triterpene saponin from Pittosporum viridiflorum from the Madagascar rainforest

Youngwan Seo et al. J Nat Prod. 2002 Jan.

Abstract

A novel triterpenoid saponin, pittoviridoside (1), which possesses an unusual 2,3,4-trisubstituted glycosidic linkage, has been isolated from Pittosporum viridiflorum using the engineered yeast strains 1138, 1140, 1353, and Sc-7 for bioactivity-guided fractionation. The structure of this compound was determined to be 3-O-[beta-D-glucopyranosyl(1-->2)]-[alpha-D-arabinopyranosyl(1-->3)],[alpha-l-arabinofuranosyl(1-->4)-beta-D-glucuronopyranosyl-21-angeloyl-22-senecioylolean-12-en-3beta,15alpha,16alpha,21beta,22alpha,28-hexol by spectral, chemical, and GC analyses. This compound showed weak cytotoxicity against the A2780 human ovarian cancer cell line.

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