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Case Reports
. 2002 Jan;88(1):67-8.
doi: 10.1016/S1081-1206(10)63596-X.

Case report of an anaphylactoid reaction to arginine

Affiliations
Case Reports

Case report of an anaphylactoid reaction to arginine

David J Resnick et al. Ann Allergy Asthma Immunol. 2002 Jan.

Abstract

Background: Arginine is an agent commonly used to evaluate adequacy of growth hormone (GH) secretion. Because arginine is a simple amino acid, it is considered safe and rarely causes adverse reactions.

Objective: To report the second anaphylactoid reaction to arginine in a child undergoing stimulation testing with arginine for assessing GH secretion.

Methods: Allergy skin testing to arginine was performed with a protocol similar to penicillin testing 4 weeks after the anaphylactoid reaction.

Results: Testing revealed a positive response to the arginine.

Conclusions: The use of intravenous arginine as a test of GH reserve remains safe and effective, but it is prudent to have the equipment and medication available to treat an allergic reaction.

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