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. 2002 Feb;18(2):60-3.
doi: 10.1016/s0168-9525(02)02591-x.

Regulatory context is a crucial part of gene function

Sabine Fessele  1 , Holger Maier, Christian Zischek, Peter J Nelson, Thomas Werner
Affiliations

Regulatory context is a crucial part of gene function

Sabine Fessele et al. Trends Genet. 2002 Feb.

Abstract

Information about the time and place of gene transcription, which until recently was only possible by extensive experimental analysis, can now be predicted through in silico analysis. Using the human RANTES/CCL5 promoter, we show that organizational features of promoters derived from promoter sequences contain information about the spatial and temporal 'functional context' of expression.

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