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. 2000 Oct;6(5):754-758.
doi: 10.3748/wjg.v6.i5.754.

Gene expression profiles in gastric mucosa of sleep deprivation rats

Gene expression profiles in gastric mucosa of sleep deprivation rats

Xi-Zhong Shen et al. World J Gastroenterol. 2000 Oct.
No abstract available

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Figures

Figure 1
Figure 1
Effect of sleep disturbance on cold-restraint stress induced (4 °C for 2 h) gastric ulceration in rats. Values are means ± SEM of 12 rats in each group; bP < 0.01, vs control group.
Figure 2
Figure 2
Effect of sleep deprivation on ethanol in duced (500 mL/L ethanol 1 mL p.o. for 2 h) gastric ulceration in rats. Error bars represent SEM, n = 10 for each group. bP < 0.01, vs control group.
Figure 3
Figure 3
cDNA array: Differential gene expression in gastric mucosa of normal control rat (A) and sleep deprivation rat (B). Sleep deprivation may decrease the following genes expression (Arrow 1-6) 1: bile-salt-stimulated lipase; 2: pancreatic lipase related protein 2 precursor; 3: triacylglycerol lipase precursor; 4: elastase 2 precursor; 5: trypsinogen II; 6: chymotrypsinogen B precursor, and increase the following genes expression (Arrow a-c) a: low-density lipoprotein receptor precursor; b: glucose transporter type 1; c: transferrin receptor protein. The dot for over expressed inducible heat shock protein 70 gene is circled.

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