Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
Comparative Study
. 1975 Jun;92(6):703-6.
doi: 10.1111/j.1365-2133.1975.tb03153.x.

Treatment of solar keratoses of the extremities with retinoic acid and 5-fluorouracil

T A Robinson, A M Kligman
Comparative Study

Treatment of solar keratoses of the extremities with retinoic acid and 5-fluorouracil

T A Robinson et al. Br J Dermatol. 1975 Jun.

Abstract

In contrast to solar keratoses of the face, twice daily application of 5% 5-fluorouracil cream was found to be incapable of destroying such lesions situated on the forearms and hands. Twice daily application of 0-1% retinoic acid was also ineffective. Combined use of these agents eradicated keratoses in all twenty subjects with numerous keratoses of the forearms; in only two was the treatment ineffective for keratoses of the hands.

PubMed Disclaimer

Publication types