Two-carrier models for mediated transport. II. Glucose and galactose equilibrium exchange experiments in human erythrocytes as a test for several two-carrier models
- PMID: 1182144
- DOI: 10.1016/0005-2736(75)90236-9
Two-carrier models for mediated transport. II. Glucose and galactose equilibrium exchange experiments in human erythrocytes as a test for several two-carrier models
Abstract
1. Equilibrium exchange of glucose and of galactose is measured in human erythrocytes over wide concentration ranges. One-site Michaelis-Menten-type kinetics are shown for the two sugars. 2. In view of the results, two of the two-carrier models discussed in paper I (Eilam, Y. (1975) Biochim. Biophys. Acta 401, 349-363), the different sequential carriers and the antiparallel simultaneous carriers, are rejected for the sugar transfer system. The antiparallel sequential carriers model is consistent with these results.
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