The effects of therapeutic radiation on colonic mucosa
- PMID: 1182679
- DOI: 10.1002/1097-0142(197509)36:3<931::aid-cncr2820360314>3.0.co;2-r
The effects of therapeutic radiation on colonic mucosa
Abstract
Low to moderate doses of therapeutic irradiation are capable of producing bizarre cytologic changes in the mucosal cells of colorectal crypts. This may be associated with eosinophilia of the lamina propria and with eosinophilic crypt abscesses. The bizarre cells generally line intact crypts and do not exhibit invasive behavior. The change subsides within 1-2 months at the dose levels studied (approximately 2000 rads).
Similar articles
-
Transitional mucosa of colon. A morphological, histochemical, and immunohistochemical study.Arch Pathol Lab Med. 1990 Jan;114(1):72-5. Arch Pathol Lab Med. 1990. PMID: 2403782
-
Palliative radiation therapy in patients with cancer of the colon and rectum.Cancer. 1970 Feb;25(2):343-6. doi: 10.1002/1097-0142(197002)25:2<343::aid-cncr2820250210>3.0.co;2-2. Cancer. 1970. PMID: 4189850 No abstract available.
-
Mucosal neuroma of the rectosigmoid colon.Gastrointest Endosc. 1986 Jun;32(3):219-20. doi: 10.1016/s0016-5107(86)71811-7. Gastrointest Endosc. 1986. PMID: 3721142 No abstract available.
-
The pros and cons of irradiation treatment of colorectal cancer.Surg Annu. 1978;10:175-90. Surg Annu. 1978. PMID: 345501 Review. No abstract available.
-
A review of the value of radiation therapy for adenocarcinoma of the rectum and sigmoid.Front Gastrointest Res. 1979;5:93-101. doi: 10.1159/000402316. Front Gastrointest Res. 1979. PMID: 387561 Review. No abstract available.
Cited by
-
Changes in neurons, neuroendocrine cells and nerve fibers in the lamina propria of irradiated bowel.Virchows Arch A Pathol Anat Histopathol. 1991;418(2):163-8. doi: 10.1007/BF01600292. Virchows Arch A Pathol Anat Histopathol. 1991. PMID: 1825364
-
Late cytokinetic abnormalities in irradiated rectal mucosa.Int J Colorectal Dis. 1990 May;5(2):98-102. doi: 10.1007/BF00298479. Int J Colorectal Dis. 1990. PMID: 2358743
-
Pathogenesis of acute radiation injury to the rectum. A prospective study in patients.Int J Colorectal Dis. 1994 Apr;9(1):23-30. doi: 10.1007/BF00304295. Int J Colorectal Dis. 1994. PMID: 8027619
-
Early proliferative defects induced by six weekly injections of 1,2-dimethylhydrazine in epithelial cells of mouse distal colon.Z Krebsforsch Klin Onkol Cancer Res Clin Oncol. 1978 May 31;91(2):205-16. doi: 10.1007/BF00284027. Z Krebsforsch Klin Onkol Cancer Res Clin Oncol. 1978. PMID: 149444 No abstract available.
-
In vivo rectal inflammatory mediator changes with radiotherapy to the pelvis.Gut. 1993 Sep;34(9):1210-4. doi: 10.1136/gut.34.9.1210. Gut. 1993. PMID: 8406156 Free PMC article.