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Review
. 2002 Feb 4;156(3):415-7.
doi: 10.1083/jcb.200112122. Epub 2002 Feb 4.

Hitchhiking fads en route to peroxisomes

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Review

Hitchhiking fads en route to peroxisomes

Suresh Subramani. J Cell Biol. .

Abstract

A unique aspect of protein translocation across the peroxisomal membrane is that folded and oligomeric proteins get across this membrane (Purdue and Lazarow, 2001). The generality of this rule, its specific features, and its mechanism are not fully understood. A paper in this issue addresses, in a very thorough fashion, the assembly, cofactor binding, and import of an oligomeric protein, acyl-CoA oxidase (Aox), into the peroxisome matrix (Titorenko et al., 2002, this issue).

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