Hitchhiking fads en route to peroxisomes
- PMID: 11827979
- PMCID: PMC2173331
- DOI: 10.1083/jcb.200112122
Hitchhiking fads en route to peroxisomes
Abstract
A unique aspect of protein translocation across the peroxisomal membrane is that folded and oligomeric proteins get across this membrane (Purdue and Lazarow, 2001). The generality of this rule, its specific features, and its mechanism are not fully understood. A paper in this issue addresses, in a very thorough fashion, the assembly, cofactor binding, and import of an oligomeric protein, acyl-CoA oxidase (Aox), into the peroxisome matrix (Titorenko et al., 2002, this issue).
Comment on
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The importin-beta binding domain of snurportin1 is responsible for the Ran- and energy-independent nuclear import of spliceosomal U snRNPs in vitro.J Cell Biol. 2002 Feb 4;156(3):467-79. doi: 10.1083/jcb.200108114. Epub 2002 Jan 28. J Cell Biol. 2002. PMID: 11815630 Free PMC article.
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References
-
- Brul, S., E.A. Wiemer, A. Westerveld, A. Strijland, R.J. Wanders, A.W. Schram, H.S. Heymans, R.B. Schutgens, H. Van den Bosch, and J.M. Tager. 1988. Kinetics of the assembly of peroxisomes after fusion of complementary cell lines from patients with the cerebro-hepato-renal (Zellweger) syndrome and related disorders. Biochem. Biophys. Res. Commun. 152:1083–1089. - PubMed
-
- Crookes, W.J., and L.J. Olsen. 1998. The effects of chaperones and the influence of protein assembly on peroxisomal protein import. J. Biol. Chem. 273:17236–17242. - PubMed
-
- Evers, M.E., V. Titorenko, W. Harder, I.J. van der Klei, and M. Veenhuis. 1996. Flavin adenine dinucleotide binding is the crucial step in alcohol oxidase assembly in the yeast Hansenula polymorpha. Yeast. 12:917–923. - PubMed
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