Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
Review
. 2002 Jan 25;108(2):165-70.
doi: 10.1016/s0092-8674(02)00626-8.

The role of PML in tumor suppression

Paolo Salomoni  1 , Pier Paolo Pandolfi
Affiliations
Free article
Review

The role of PML in tumor suppression

Paolo Salomoni et al. Cell. .
Free article

Abstract

The PML gene, involved in the t(15;17) chromosomal translocation of acute promyelocytic leukemia (APL), encodes a protein which localizes to the PML-nuclear body, a subnuclear macromolecular structure. PML controls apoptosis, cell proliferation, and senescence. Here, we review the current understanding of its role in tumor suppression.

PubMed Disclaimer

MeSH terms

LinkOut - more resources