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Comparative Study
. 2002;17 Suppl 2(Suppl 2):S75-8.
doi: 10.1002/mds.10065.

Dry eye, blinking, and blepharospasm

Craig Evinger  1 , Jian-Bin Bao, Alice S Powers, Iris S Kassem, Edward J Schicatano, Victor M Henriquez, Kavita R Peshori
Affiliations
Comparative Study

Dry eye, blinking, and blepharospasm

Craig Evinger et al. Mov Disord. 2002.
No abstract available

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Figures

FIG. 1
FIG. 1
Blink modifications associated with dry eye. A: A single, twice threshold intensity stimulus to the supraorbital branch of the trigeminal nerve (SO↑) evokes a reflex blink and additional blinks, blink oscillations, which occur with a nearly constant interblink interval. Each trace is a single trial showing upper eyelid position. B: Graph showing the average number of blink oscillations per trial (Osc/Trial), interblink oscillation interval (Pk Osc), blink oscillation duration (Osc Dur), amplitude of blink oscillations (Osc Amp), amplitude of reflex blinks (Ref Amp), reflex blink duration (Ref Dur), and reflex blink excitability (Ref Exct) for five dry eye subjects relative to age-matched controls. C: Average reflex blink excitability for all four interstimulus intervals relative to age-matched control subjects as a function of blink oscillations per trial relative to age-matched control subjects for the five dry eye subjects. The line is the best-fit linear regression (y = 0.933, x = 0.056, r2 = 0.67).
FIG. 2
FIG. 2
Effect of high-intensity stimulation (10× threshold) to the supraorbital branch of the trigeminal nerve on subsequent reflex blinks. Before high-intensity treatment (Pre), pairs of twice threshold intensity stimuli to the supraorbital branch of the trigeminal nerve (SO dashed lines) with a 500-msec interstimulus interval elicited unequal amplitude reflex blinks. After high-intensity treatment (Post), the same stimuli elicited nearly equal amplitude reflex blinks and a blink oscillation. Each trace is a single record of upper eyelid position.
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