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. 2002 Feb 12;58(3):471-3.
doi: 10.1212/wnl.58.3.471.

Multiple sclerosis-associated retrovirus (MSRV) in Sardinian MS patients

A Dolei  1 , C Serra, G Mameli, M Pugliatti, G Sechi, M C Cirotto, G Rosati, S Sotgiu
Affiliations

Multiple sclerosis-associated retrovirus (MSRV) in Sardinian MS patients

A Dolei et al. Neurology. .

Abstract

Blood and CSF of Sardinian patients with MS and neurologic control subjects were tested for MS-associated retrovirus (MSRV). CSF detection in MS was 50% at clinical onset, increasing with temporal disease progression, and 40% in control subjects. In blood, MSRV was detected in all MS patients, in most patients with inflammatory neurologic diseases, and rarely in healthy blood donors. MSRV may represent a marker of neurologic diseases of inflammatory origin.

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