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Review
. 2002 Feb;28(1):1-15, v.
doi: 10.1016/s0889-857x(03)00066-8.

Rheumatoid arthritis. The genetic components

Damini Jawaheer  1 , Peter K Gregersen
Affiliations
Review

Rheumatoid arthritis. The genetic components

Damini Jawaheer et al. Rheum Dis Clin North Am. 2002 Feb.

Abstract

Rheumatoid arthritis is a multifactorial disease, with genetic, environmental, and stochastic components to its susceptibility. The search for susceptibility genes is still in progress. Preliminary results suggest the involvement of multiple genes, each with relatively modest effect. Genes within the major histocompatibility complex appear to have the strongest influence on disease susceptibility.

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