Inflammation in acute coronary syndromes
- PMID: 11847151
- PMCID: PMC1767031
- DOI: 10.1136/heart.87.3.201
Inflammation in acute coronary syndromes
Abstract
Extensive evidence supports a pathogenic role for both local and systemic inflammation in acute coronary syndromes. However, several important questions remain unanswered. Is the observed inflammatory process a precursor or a consequence of coronary plaque rupture? Is the inflammatory component of unstable coronary disease a potential therapeutic target? Finally, do infectious agents have a pathogenic role in coronary atherosclerosis and acute coronary syndromes?
References
-
- Fuster V, Badimon L, Badimon J, et al. The pathogenisis of coronary artery disease and the acute coronary syndromes. N Engl J Med 1992;326:242–50. - PubMed
-
- Kohchi K, Takebayashi S, Hiroki T, et al. Significance of adventitial inflammation of the coronary artery in patients with unstable angina: results at autopsy. Circulation 1985;4:709–16. - PubMed
-
- Van der Wal AC, Becker AE, van der Loos CM, et al. Site of intimal rupture or erosion of thrombosed coronary atherosclerotic plaques is characterised by an inflammatory process irrespective of the dominant plaque morphology. Circulation 1994;89:36–44. - PubMed
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