Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
. 2002 Mar;46(3):866-70.
doi: 10.1128/AAC.46.3.866-870.2002.

In vitro activities of the des-fluoro(6) Quinolone BMS-284756 against aerobic and anaerobic pathogens isolated from skin and soft tissue animal and human bite wound infections

Ellie J C Goldstein  1 , Diane M Citron, C Vreni Merriam, Yumi A Warren, Kerin L Tyrrell, Helen Fernandez
Affiliations

In vitro activities of the des-fluoro(6) Quinolone BMS-284756 against aerobic and anaerobic pathogens isolated from skin and soft tissue animal and human bite wound infections

Ellie J C Goldstein et al. Antimicrob Agents Chemother. 2002 Mar.

Abstract

BMS-284756, a new des-fluoro(6) quinolone, was very active against 240 aerobic and 180 anaerobic isolates from bite victims. It inhibited 403 of 420 (96%) isolates, including those of Moraxella spp., CDC group EF-4, and Eikenella corrodens at < or = 2 microg/ml and those of all Pasteurella spp. and Bergeyella zoohelcum at < or = 0.015 microg/ml. Fusobacterium russii and 6 of 11 Fusobacterium nucleatum isolates of animal bite origin were resistant, but isolates of human bite origin were susceptible, which suggests that they were of a different subspecies.

PubMed Disclaimer

Similar articles

See all similar articles

Cited by

See all "Cited by" articles

References

    1. Alexander, C. J., D. M. Citron, S. H. Gerardo, M. C. Claros, D. Talan, and E. J. C. Goldstein. 1997. Characterization of saccharolytic Bacteroides and Prevotella isolates from infected dog and cat bite wounds in humans. J. Clin. Microbiol. 35:406-411. - PMC - PubMed
    1. Chambers, H. F., and H. C. Neu. 1995. Penicillins, p. 233-245. In G. L. Mandel, J. E. Bennett, and R. Dolin (ed.), Principles and practice of infectious diseases, 4th ed. Churchill Livingstone Inc., New York, N.Y.
    1. Fung-Tomc, J. C., B. Minassian, B. Kolek, E. Huczko, L. Aleksunes, T. Stickle, T. Washo, E. Gradelski, L. Valera, and D. P. Bonner. 2000. Antibacterial spectrum of a novel des-fluoro(6) quinolone, BMS-284756. Antimicrob. Agents Chemother. 44:3351-3356. - PMC - PubMed
    1. Goldstein, E. J. C. 1992. Bite wounds and infection. Clin. Infect. Dis. 14:633-640. - PubMed
    1. Goldstein, E. J. C. 1998. New horizons in the bacteriology, antimicrobial susceptibility and therapy of animal bite wounds. J. Med. Microbiol. 47:1-3. - PubMed

Publication types

LinkOut - more resources