Monoaminergic neurotoxins: are they selective?
- PMID: 1185164
- DOI: 10.1007/BF01670127
Monoaminergic neurotoxins: are they selective?
Abstract
Introduction of 6-hydroxydopamine into the cerebrospinal fluid produces a selective destruction of adrenergic pathways. However, the selectivity of interstitial injections of 6-hydroxydopamine for catecholamine elements is critically dependent upon the dose and volume of injection must be evaluated by biochemical and cytochemical indices.
Similar articles
-
Effects of intraventricular injection of 6-hydroxydopamine in the developing kitten. II. On the central monoaminergic innervation.Brain Res. 1979 Jan 19;160(3):461-78. doi: 10.1016/0006-8993(79)91073-4. Brain Res. 1979. PMID: 421125 No abstract available.
-
Effect of selective destruction of central and peripheral catecholamine-containing neurones with 6-hydroxydopamine on catecholamine excretion in the rat.Br J Pharmacol. 1974 Feb;50(2):265-70. doi: 10.1111/j.1476-5381.1974.tb08571.x. Br J Pharmacol. 1974. PMID: 4425765 Free PMC article.
-
[Effect of the intracisternal administration of the neurotoxins 6-hydroxydopamine and 5,7-dihydroxytryptamine on the formation of the passive avoidance reaction and the biogenic amine level in the brain of rats].Fiziol Zh SSSR Im I M Sechenova. 1988 Jul;74(7):920-3. Fiziol Zh SSSR Im I M Sechenova. 1988. PMID: 3141223 Russian.
-
Theories of the dorsal bundle extinction effect.Brain Res. 1979 Jul;180(1):107-37. doi: 10.1016/0165-0173(79)90018-3. Brain Res. 1979. PMID: 385111 Review.
-
6-hydroxydopamine destruction of central adrenergic neurones prevents or reverses developing DOCA-salt hypertension in rats.J Neural Transm. 1977;40(2):149-58. doi: 10.1007/BF01250565. J Neural Transm. 1977. PMID: 323422 Review.
References
MeSH terms
Substances
LinkOut - more resources
Full Text Sources