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. 1975;37(3):183-7.
doi: 10.1007/BF01670127.

Monoaminergic neurotoxins: are they selective?

Monoaminergic neurotoxins: are they selective?

F E Bloom. J Neural Transm. 1975.

Abstract

Introduction of 6-hydroxydopamine into the cerebrospinal fluid produces a selective destruction of adrenergic pathways. However, the selectivity of interstitial injections of 6-hydroxydopamine for catecholamine elements is critically dependent upon the dose and volume of injection must be evaluated by biochemical and cytochemical indices.

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