Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
. 2002 Feb;77(2):81-6.

[Selective ophthalmic artery fibrinolysis in acute central retinal artery occlusion]

[Article in Spanish]
F J Fernández  1 , S Guelbenzu, C Barrena, J M Larrosa, F J Gonzalvo, B Melcon, F M Honrubia
Affiliations
  • PMID: 11854859

[Selective ophthalmic artery fibrinolysis in acute central retinal artery occlusion]

[Article in Spanish]
F J Fernández et al. Arch Soc Esp Oftalmol. 2002 Feb.

Abstract

Purpose: To evaluate efficacy and reliability of local intra-arterial fibrinolysis (LIF) in Retinal Central Artery Occlusion (RCAO).

Material and method: We have studied 12 patients with RCAO. Seven patients (group I) were treated with conventional therapy and 5 patients (group II) underwent treatment with urokinase via transcutaneous femoral catheter into the ophthalmic artery. Thereafter patients received heparin sulfate for 3 days.

Results: Mean follow up was 14 months and mean time from onset of symptoms to the beginning of therapy was 11 hours. One patient in group I showed improvement of visual acuity (from counting fingers to 0.1). In all patients in group II there was angiographic evidence of improved perfusion of retinal arteries and 4 patients (80%) showed improvement in visual acuity. The best results were obtained when LIF was performed before 10 hours after onset of symptoms. No complications were observed after the fibrinolysis treatment.

Conclusion: LIF in ophtalmic arteries for the treatment of RCAO reduces dosage of fibrinolytic agents and becomes a safe and useful treatment during the first hours post RCAO.

PubMed Disclaimer

Publication types

Substances