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. 1975 Mar;2(1):28-35.

Quantitation of gold in skin in chrysiasis

D Jeffery, D F Biggs, J S Percy, A S Russell
  • PMID: 1185732

Quantitation of gold in skin in chrysiasis

D Jeffery et al. J Rheumatol. 1975 Mar.

Abstract

Skin, plasma, hair, and nail gold levels were determined in three groups of patients with rheumatoid arthritis comprising: I. Three patients on long term gold therapy exhibiting altered skin pigmentation (chrysiasis); II. Five patients on long term gold therapy exhibiting normal skin pigmentation; III. Two patients starting gold therapy. Group I had higher skin gold levels (50-140 mug/g) than Group II (7.5-13 mug/g) while Group II had minimal levels. Hair and nail gold levels were not much higher than gold levels in non-gold treated individuals. The possible role of skin in the storage or excretion of gold is discussed.

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