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Review
. 2002 Feb 23;324(7335):466-9.
doi: 10.1136/bmj.324.7335.466.

Peripheral neuropathy

Richard A C Hughes  1
Affiliations
Review

Peripheral neuropathy

Richard A C Hughes. BMJ. .
No abstract available

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Figures

Figure
Figure
Muscle action potentials after distal and proximal stimulation of a nerve to a muscle such as abductor pollicis brevis. The upper trace of each pair is the record after distal stimulation. In the normal nerve the distal motor latency is short and nerve conduction velocity rapid (>50m/sec). In demyelinating neuropathy the distal motor latency is prolonged and nerve conduction velocity slowed to less than 80% of normal. In axonal neuropathy the action potential is reduced, but the distal motor latency and nerve conduction velocity are unaffected. Multifocal abnormalities with normal conduction velocity suggest multiple mononeuropathy
See this image and copyright information in PMC

References

    1. Martyn CN, Hughes RAC. Epidemiology of peripheral neuropathy. J Neurol Neurosurg Psychiatry. 1997;62:310–318. - PMC - PubMed
    1. Boulton AJ, Gries FA, Jervell JA. Guidelines for the diagnosis and outpatient management of diabetic peripheral neuropathy. Diabet Med. 1998;15:508–514. - PubMed
    1. Rosenberg NR, Portegies P, de Visser M, Vermeulen M. Diagnostic investigation of patients with chronic polyneuropathy: evaluation of a clinical guideline. J Neurol Neurosurg Psychiatry. 2001;71:205–209. - PMC - PubMed
    1. Hughes RAC, Raphael J-C, Swan AV, van Doorn PA. Intravenous immunoglobulin for Guillain-Barré syndrome (Cochrane review). Cochrane Database Syst Rev 2001;(3):CD20014. - PubMed
    1. Van Koningsveld R, van der Meché FGA, Schmitz PIM, van Doorn PA. Combined therapy of intravenous immunoglobulin and methylprednisolone in patient with Guillain-Barré syndrome. J Peripheral Nervous System. 2000;6:186–187.

MeSH terms