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. 2002:2:4.
doi: 10.1186/1471-244x-2-4. Epub 2002 Jan 22.

Current practices in managing acutely disturbed patients at three hospitals in Rio de Janeiro-Brazil: a prevalence study

Gisele Huf  1 , Evandro da Silva Freire Coutinho, Hugo M Fagundes Jr, Edmar S Oliveira, Jose Ramon R A Lopez, Marcio Gewandszajder, Andreia da Luz Carvalho, Alexandre Keusen, Clive E Adams
Affiliations

Current practices in managing acutely disturbed patients at three hospitals in Rio de Janeiro-Brazil: a prevalence study

Gisele Huf et al. BMC Psychiatry. 2002.

Abstract

Background: The medical management of aggressive and violent behaviour is a critical situation for which there is little evidence. In order to prepare for a randomised trial, due to start in the psychiatric emergency rooms of Rio de Janeiro in 2001, a survey of current practice was necessary.

Methods: A seven day survey of pharmacological management of aggressive people with psychosis in the emergency rooms of all four public psychiatric hospitals in Rio de Janeiro, Brazil.

Results: In one hospital data were not available. Of the 764 people with psychosis attending these ERs, 74 were given IM medication for rapid tranquillisation (9.7%, 2.1/week/100,000). A haloperidol-promethazine mix (with or without other drugs) was used for the majority of patients (83%).

Conclusion: The haloperidol-promethazine mix, given intramuscularly for rapid tranquilization, is prevalent in Rio, where it is considered both safe and efficient. However, scientific evaluation of all pharmacological approaches to rapid tranquilization of psychotic people is inadequate or incomplete and a randomized trial of IM haloperidol-promethazine is overdue.

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