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Review
. 2002 Feb;9(2):209-11.
doi: 10.1016/s1097-2765(02)00463-x.

Opening chromatin

Stavros Lomvardas  1 , Dimitris Thanos
Affiliations
Free article
Review

Opening chromatin

Stavros Lomvardas et al. Mol Cell. 2002 Feb.
Free article

Abstract

How the transcriptional apparatus gains access to and subsequently opens compacted chromatin has remained a mystery. Now in this issue of Molecular Cell, Zaret and coworkers show that chromatin opening in vitro is not mediated by the classical chromatin remodeling machines but instead occurs through specific transcription factor-histone interactions.

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