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Review
. 2002 Feb;9(2):213-24.
doi: 10.1016/s1097-2765(02)00443-4.

CtBP, an unconventional transcriptional corepressor in development and oncogenesis

G Chinnadurai  1
Affiliations
Free article
Review

CtBP, an unconventional transcriptional corepressor in development and oncogenesis

G Chinnadurai. Mol Cell. 2002 Feb.
Free article

Abstract

CtBP family proteins are conserved among vertebrates and invertebrates and function as transcriptional corepressors. They repress transcription in a histone deacetylase-dependent or -independent manner. CtBPs play important roles during development and oncogenesis. In this review, their unusual properties, the mechanisms of transcriptional repression, regulation, and their biological functions are discussed.

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