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Case Reports
. 2002 Feb;140(2):250-1.
doi: 10.1067/mpd.2002.121934.

Varicella-zoster virus acquired at 4 months of age reactivates at 24 months and causes encephalitis

Elena Chiappini  1 , Giuseppe Calabri, Luisa Galli, Giuseppe Salvi, Maurizio de Martino
Affiliations
Case Reports

Varicella-zoster virus acquired at 4 months of age reactivates at 24 months and causes encephalitis

Elena Chiappini et al. J Pediatr. 2002 Feb.

Abstract

Varicella-zoster virus (VZV) reactivation in the brain caused encephalitis in a 2-year-old immunocompetent child who had chickenpox 20 months before. Radiologic findings were consistent with large to medium-vessel-vasculitis. VZV-DNA was detected in cerebrospinal fluid. Early acquisition of VZV may predispose to major neurologic complications that can occur years after the primary infection.

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