[Sudden death of a two-year-old boy with influenza A virus infection: study of an autopsy case]
- PMID: 11865549
- PMCID: PMC7126749
- DOI: 10.1016/s0929-693x(01)00693-5
[Sudden death of a two-year-old boy with influenza A virus infection: study of an autopsy case]
Abstract
Influenza A virus infections are common in childhood and infancy and are often underdiagnosed while serious or lethal forms are rare.
Case-report: We describe a case of sudden death in a two-year-old boy. Pathologic findings at autopsy were consistent with Myxovirus influenzae A virus infection and the virus was isolated by post mortem PCR.
Conclusion: In the case of sudden death in infants, especially if pathologic findings are compatible with a viral infection, PCR may allow identification of the causative virus.
La grippe de l’enfant est fréquente mais passe souvent inaperçue. Les formes gravissimes ou létales sont en revanche exceptionnelles.
Observation. – Nous rapportons une observation de décès brutal d’un enfant de 23 mois chez lequel le virus Influenza A a été isolé postmortem par polymerase chain reaction (PCR) dans le poumon et dont les lésions anatomopathologiques étaient celles décrites dans la grippe maligne.
Conclusion. – Devant un tableau de décès non expliqué voire une mort subite du nourrisson ou du jeune enfant, les causes infectieuses en particulier virales doivent être cherchées soigneusement avec recherche virale par PCR recommandée, les autres techniques pouvant rester négatives.
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