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. 2002 Mar;222(3):789-93.
doi: 10.1148/radiol.2223010531.

Morphologic phenotyping with MR microscopy: the visible mouse

G Allan Johnson  1 , Gary P Cofer, Sally L Gewalt, Laurence W Hedlund
Affiliations

Morphologic phenotyping with MR microscopy: the visible mouse

G Allan Johnson et al. Radiology. 2002 Mar.

Abstract

A method for rapid morphologic phenotyping is demonstrated by using magnetic resonance microscopy. Whole fixed C57BL/6J mice were imaged at 110-microm isotropic resolution; limited volumes of the intact specimen, at 50-microm isotropic resolution; and isolated organs, at 25-microm isotropic resolution. The three-dimensional imaging technique was applied to uricase knockout mice to demonstrate the method for the evaluation of morphologic phenotype.

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