[Is heart rate reduction beneficial to patients with heart insufficiency? Focus on beta-blockade]
- PMID: 11871210
[Is heart rate reduction beneficial to patients with heart insufficiency? Focus on beta-blockade]
Abstract
The aim of this review was to assess the effect of pharmacological reduction of the heart rate on prognosis in patients with chronic heart failure. Although a high heart rate is associated with a reduced life expectancy and causes a number of unwanted pathophysiological effects on the failing heart, there is no documentation that the beneficial effect of beta-blockers or other heart failure agents on survival is mediated through a reduction in heart rate.
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