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Comment
. 2002 Mar 1;295(5560):1651-3.
doi: 10.1126/science.1070163.

Does BDNF have pre- or postsynaptic targets?

Toshiya Manabe  1
Affiliations
Comment

Does BDNF have pre- or postsynaptic targets?

Toshiya Manabe. Science. .

Abstract

A type of synaptic plasticity in the brain called long-term potentiation (LTP) is thought to form the molecular basis of learning and memory. In a Perspective, Manabe discusses new findings (Kovalchuk et al.) showing brain-derived neurotropic factor modulates LTP by binding to TrkB receptors on the postsynaptic neuron.

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