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. 1975 Oct;2(10):1931-9.
doi: 10.1093/nar/2.10.1931.

Distribution of the modified nucleoside Q and its derivatives in animal and plant transfer RNA's

H Kasai, Y Kuchino, K Nihei, S Nishimura
Free PMC article

Distribution of the modified nucleoside Q and its derivatives in animal and plant transfer RNA's

H Kasai et al. Nucleic Acids Res. 1975 Oct.
Free PMC article

Abstract

The modified nucleoside, 7-(4,5-cis-dihydroxy-1-cyclopenten-3-yl-aminomethyl)-7-deazaguanosine, designated as Q, and its derivative, Q*, were found in tRNA's from various organisms, including several mammalian tissues, other animals such as starfish, lingula and hagfish, and wheat germ. Q isolated from rat liver tRNA was found to be identical with E. coli Q by mass spectrometry and thin-layer chromatography. Thus the rare modified nucleoside Q originally isolated from E. coli tRNA, is widely distributed in various organisms. Analysis of the mass spectrum of Q* suggested that it has a different side chain from Q.

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