Itraconazole was as effective as amphotericin B for fever and neutropenia in cancer and led to fewer adverse events

Affiliations

Comment

Elizabeth J Phillips. ACP J Club. 2002 Mar-Apr.

. 2002 Mar-Apr;136(2):58.

¹ Sunnybook and Women's College Health Sciences Center, Toronto, Ontario, Canada.

No abstract available

Comment on

Intravenous and oral itraconazole versus intravenous amphotericin B deoxycholate as empirical antifungal therapy for persistent fever in neutropenic patients with cancer who are receiving broad-spectrum antibacterial therapy. A randomized, controlled trial.
Boogaerts M, Winston DJ, Bow EJ, Garber G, Reboli AC, Schwarer AP, Novitzky N, Boehme A, Chwetzoff E, De Beule K; Itraconazole Neutropenia Study Group. Boogaerts M, et al. Ann Intern Med. 2001 Sep 18;135(6):412-22. doi: 10.7326/0003-4819-135-6-200109180-00010. Ann Intern Med. 2001. PMID: 11560454 Clinical Trial.