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. 1975 Sep-Oct;27(5):567-77.

Studies on absorption and elimination of drugs. Part IV. Computer evaluation of pharmacokinetic parameters of the two compartment open model

  • PMID: 1187459

Studies on absorption and elimination of drugs. Part IV. Computer evaluation of pharmacokinetic parameters of the two compartment open model

M Ksiezyk et al. Pol J Pharmacol Pharm. 1975 Sep-Oct.

Abstract

A simple programme was written in ALGOL 1204 for the Polish digital computer ODRA 1204. It permits the fitting of the biexponential equation C = Ae-alphat+Be-betat to the observed plasma or serum concentration data of a drug after a single iv injection.

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