Studies on absorption and elimination of drugs. Part IV. Computer evaluation of pharmacokinetic parameters of the two compartment open model
- PMID: 1187459
Studies on absorption and elimination of drugs. Part IV. Computer evaluation of pharmacokinetic parameters of the two compartment open model
Abstract
A simple programme was written in ALGOL 1204 for the Polish digital computer ODRA 1204. It permits the fitting of the biexponential equation C = Ae-alphat+Be-betat to the observed plasma or serum concentration data of a drug after a single iv injection.