[The manifestations of 496 cases with thyroid-related immune orbitopathy and normal thyroid function]

Abstract

Objective: To observe the clinical manifestations of thyroid-related immune orbitopathy (TRIO) with normal thyroid function.

Methods: 496 cases with TRIO were collected from 1973 to 1994 and their clinical manifestations were analyzed.

Results: The clinical manifestations showed that males are more than females. The disease occurred in middle aged persons with unilateral exophthalmos as the primary early manifestation. Most of the cases had the signs of eyelids and extraocular muscle involvement.

Conclusions: The thyroid-related immune orbitopathy with normal thyroid function can be named thyroid-related immune orbitopathy-II. The clinical characteristics of this disease are unilateral, of signs of eyelids, exophthalmos and enlargement of eye muscles. The pseudo-tumors of the orbit are mainly considered for differential diagnosis.