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Review
. 2002 Feb;4(2):225-35.
doi: 10.1016/s1286-4579(01)01534-9.

Actinobacillus pleuropneumoniae: pathobiology and pathogenesis of infection

Janine T Bossé  1 , Håkan Janson, Brian J Sheehan, Amanda J Beddek, Andrew N Rycroft, J Simon Kroll, Paul R Langford
Affiliations
Free article
Review

Actinobacillus pleuropneumoniae: pathobiology and pathogenesis of infection

Janine T Bossé et al. Microbes Infect. 2002 Feb.
Free article

Abstract

Actinobacillus pleuropneumoniae causes porcine pleuropneumonia, a highly contagious disease for which there is no effective vaccine. This review considers how adhesins, iron-acquisition factors, capsule and lipopolysaccharide, RTX cytotoxins and other potential future vaccine components contribute to colonisation, to avoidance of host clearance mechanisms and to damage of host tissues.

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