Actinobacillus pleuropneumoniae: pathobiology and pathogenesis of infection
- PMID: 11880056
- DOI: 10.1016/s1286-4579(01)01534-9
Actinobacillus pleuropneumoniae: pathobiology and pathogenesis of infection
Abstract
Actinobacillus pleuropneumoniae causes porcine pleuropneumonia, a highly contagious disease for which there is no effective vaccine. This review considers how adhesins, iron-acquisition factors, capsule and lipopolysaccharide, RTX cytotoxins and other potential future vaccine components contribute to colonisation, to avoidance of host clearance mechanisms and to damage of host tissues.
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