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. 2001 Dec;72(12A):1365-9.

[Serum and peritoneal fluid CA-125 concentration in women with endometriosis]

[Article in Polish]
D Kraśnicki  1
Affiliations
  • PMID: 11883280

[Serum and peritoneal fluid CA-125 concentration in women with endometriosis]

[Article in Polish]
D Kraśnicki. Ginekol Pol. 2001 Dec.

Abstract

Objective: To evaluate the clinical utility of CA-125 measurements in peritoneal fluid (PF) as an indicator of endometriosis.

Design: CA-125 levels in paired serum and peritoneal fluid were assessed by IMx CA-125 Assay (ABBOTT).

Patients: 107 women with and without endometriosis, undergoing laparoscopy during the luteal phase of the menstrual cycle were selected for the study.

Results: CA-125 levels in peritoneal fluid were higher than those found in serum and were significantly elevated (P < 0.05) in comparison to the control group. In women with endometriosis stage I-II and stage III-IV. CA-125 levels in serum were increased only in stage III-IV.

Conclusions: The sensitivity of the peritoneal fluid CA-125 test for endometriosis is higher than the respective serum test. The measurement of CA-125 levels in PF could be useful in the detection of the early stage endometriosis, which seems to be missed by the CA-125 serum test.

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