Review
doi: 10.1016/s0021-9150(01)00677-3.
Dynamics of reverse cholesterol transport: protection against atherosclerosis
Affiliations
- PMID: 11888506
- DOI: 10.1016/s0021-9150(01)00677-3
Item in Clipboard
Review
Dynamics of reverse cholesterol transport: protection against atherosclerosis
Atherosclerosis.
2002 Apr.
Abstract
This review considers the antiatherogenic function of high density lipoprotein (HDL) from the point of view of its dynamics within the sequential steps of reverse cholesterol transport (RCT). It is postulated that the efficiency of cholesterol flux through the RCT pathways is clinically more relevant than the HDL cholesterol concentration. The particular role of pre-beta(1)-HDL is reviewed drawing attention to the relationship between its concentration and the flux of cholesterol through the RCT system.
Similar articles
-
Is reverse cholesterol transport a misnomer for suggesting its role in the prevention of atheroma formation?Atherosclerosis. 1995 Jul;116(1):1-14. doi: 10.1016/0021-9150(95)05531-z. Atherosclerosis. 1995. PMID: 7488324 Review.
-
Low high-density lipoprotein cholesterol: physiological background, clinical importance and drug treatment.Drugs. 2003;63(18):1907-45. doi: 10.2165/00003495-200363180-00003. Drugs. 2003. PMID: 12930163 Review.
-
Have we forgotten the pivotal role of high-density lipoprotein cholesterol in atherosclerosis prevention?Curr Med Res Opin. 2005 Feb;21(2):299-306. doi: 10.1185/030079905X26216. Curr Med Res Opin. 2005. PMID: 15802001 Review.
-
Cholesterol efflux and reverse cholesterol transport.Handb Exp Pharmacol. 2015;224:181-206. doi: 10.1007/978-3-319-09665-0_4. Handb Exp Pharmacol. 2015. PMID: 25522988 Review.
-
Reverse cholesterol transport in familial hypercholesterolemia.Curr Opin Lipidol. 2012 Aug;23(4):377-85. doi: 10.1097/MOL.0b013e328353ef07. Curr Opin Lipidol. 2012. PMID: 22510809 Review.
Cited by
-
HDL enhances oxidation of LDL in vitro in both men and women.Lipids Health Dis. 2005 Oct 20;4:25. doi: 10.1186/1476-511X-4-25. Lipids Health Dis. 2005. PMID: 16242018 Free PMC article.
-
Chronic myeloid leukemia patients sensitive and resistant to imatinib treatment show different metabolic responses.PLoS One. 2010 Oct 8;5(10):e13186. doi: 10.1371/journal.pone.0013186. PLoS One. 2010. PMID: 20949032 Free PMC article.
-
Modified high-density lipoprotein modulates aldosterone release through scavenger receptors via extra cellular signal-regulated kinase and Janus kinase-dependent pathways.Mol Cell Biochem. 2012 Jul;366(1-2):1-10. doi: 10.1007/s11010-012-1274-2. Epub 2012 Mar 1. Mol Cell Biochem. 2012. PMID: 22382638
-
Combined effects of a high-fat diet and chronic valproic acid treatment on hepatic steatosis and hepatotoxicity in rats.Acta Pharmacol Sin. 2014 Mar;35(3):363-72. doi: 10.1038/aps.2013.135. Epub 2014 Jan 20. Acta Pharmacol Sin. 2014. PMID: 24442146 Free PMC article.
-
Rosuvastatin 20 mg restores normal HDL-apoA-I kinetics in type 2 diabetes.J Lipid Res. 2009 Jun;50(6):1209-15. doi: 10.1194/jlr.P800040-JLR200. Epub 2009 Jan 22. J Lipid Res. 2009. PMID: 19168444 Free PMC article. Clinical Trial.
Publication types
MeSH terms
Substances
LinkOut - more resources
Full Text Sources
Other Literature Sources
Medical
