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. 2001 Dec;94(5):375-7.

[Particular profile of the zymodemes of Leishmania infantum causing visceral leishmaniasis in Tunisia]

[Article in French]
K Aoun  1 , A Bouratbine, Z Harrat, M Belkaïd, S Bel Hadj Ali
Affiliations
  • PMID: 11889934

[Particular profile of the zymodemes of Leishmania infantum causing visceral leishmaniasis in Tunisia]

[Article in French]
K Aoun et al. Bull Soc Pathol Exot. 2001 Dec.

Abstract

The isoenzymatic typing of 16 stocks of Leishmania, isolated from Tunisian visceral leishmaniasis (VL) cases, revealed that all strains belonged to Leishmania (L.) infantum species. Although zymodeme MON-1 was predictably the most frequent (9 cases), it came as a surprise that L. infantum MON-24 was responsible of about third of cases. This latter zymodeme, while previously reported in Tunisia, Algeria and Spain, was assumed to be a dermotropic and the few cases of VL that it caused occurred always in HIV infected patients. L. infantum MON-80, occasionally reported during both cutaneous and VL of immunocompetent infants was identified in 2 patients. This report confirms that in addition to the more common L. infantum MON-1, zymodeme MON-24 has a substantial role in generating VL in immunocompetent infants in Tunisia.

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