Review
doi: 10.1016/s0955-0674(02)00313-7.
Live-cell fluorescent biosensors for activated signaling proteins
Affiliations
- PMID: 11891115
- DOI: 10.1016/s0955-0674(02)00313-7
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Review
Live-cell fluorescent biosensors for activated signaling proteins
Curr Opin Cell Biol.
2002 Apr.
Abstract
A new generation of live-cell fluorescent biosensors enables us to go beyond visualization of protein movements, to quantify the dynamics of many different protein activities. Alternate approaches can report post-translational modifications, ligand interactions and conformational changes, revealing how the location and subtle timing of protein activity controls cell behavior.
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