Postoperative improvement of hypertension in primary aldosteronism and Cushing's syndrome

Abstract

In 24 cases of primary aldosteronism and 30 cases of Cushing's syndrome, the incidence of preoperative hypertension and postoperative improvement of hypertension was investigated. All the cases of primary aldosteronism showed preoperative hypertension. Postoperative improvement of hypertension was observed in 21 out of those 24 cases. In 14 of these 21 cases, hypertension improved within 1 month postoperatively. In Cushing's syndrome, 23 out of 30 cases showed preoperative hypertension which improved in 20 cases postoperatively. They needed longer periods of time before improvement of hypertension than the cases of primary aldosteronism. The pathological findings in renal biopsy specimens seem to be correlated with postoperative improvement of hypertension in both diseases.