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Review
. 2001 May;1(3):235-41.
doi: 10.1007/s11882-001-0010-x.

Grading the severity of allergic rhinitis for treatment strategy and drug study purposes

M Okuda  1 ; US Food and Drug Administration (FDA)
Affiliations
Review

Grading the severity of allergic rhinitis for treatment strategy and drug study purposes

M Okuda et al. Curr Allergy Asthma Rep. 2001 May.

Abstract

Grading the severity of rhinitis symptoms is essential for the evaluation of drug efficacy. However, a uniform grading system has not been standardized. A review of 44 journal articles and symposia from Japan, Copenhagen, and the World Health Organization indicates major differences among systems. All except the World Health Organization used a sum of rhinitis scores. The lack of standardization limits comparisons of subjective symptom changes after comparable treatments. Corrective measures include the use of evidence-based definitions of independent nasal symptoms, avoidance of biases in evaluation, and establishment of international consensus for a standardized scale in this era of globalization.

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