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. 2002 Mar 21;4(6):995-7.
doi: 10.1021/ol020023d.

Synthesis, conformational analysis, and bioassay of 9,10-didehydroepothilone D

James D White  1 , Kurt F Sundermann, Markus Wartmann
Affiliations

Synthesis, conformational analysis, and bioassay of 9,10-didehydroepothilone D

James D White et al. Org Lett. .

Abstract

[reaction: see text] 9,10-Didehydroepothilone D was synthesized, its conformation was studied, and its tubulin polymerization and antiproliferative activity were compared with that of epothilone D and certain analogues.

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