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Review
. 2002 Mar;121(3 Suppl):7S-13S.
doi: 10.1378/chest.121.3_suppl.7s-a.

Asthma genetics

William Osmond Charles Cookson  1
Affiliations
Review

Asthma genetics

William Osmond Charles Cookson. Chest. 2002 Mar.

Abstract

Asthma is the most common chronic childhood disease in developed nations and is a complex disease that has high social and economic costs. Asthma and its associated intermediate phenotypes are under a substantial degree of genetic control. Identifying the genes underlying asthma offers a means of better understanding its pathogenesis, with the promise of improving preventive strategies, diagnostic tools, and therapies. A number of chromosomal regions containing genes influencing asthma and atopy have been identified consistently by different groups, and a role for several candidate genes has been established.

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