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Review
. 2002 Feb;29(1 Suppl 3):36-9.
doi: 10.1053/sonc.2002.30748.

Brief communication: use of the multitargeted antifolate pemetrexed (Alimta) in genitourinary cancer

Affiliations
Review

Brief communication: use of the multitargeted antifolate pemetrexed (Alimta) in genitourinary cancer

Jean-Louis Misset. Semin Oncol. 2002 Feb.

Abstract

Pemetrexed (Alimta, LY231514) is a novel, multitargeted antifolate that is broadly active in a wide variety of solid tumors, including genitourinary malignancies. This agent has also shown clinically relevant activity in combination with other agents, including gemcitabine (Gemzar; Eli Lilly and Company, Indianapolis, IN). Further investigation is warranted in advanced disease and adjuvant settings.

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