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Comparative Study
. 1975 Sep 12;47(2):145-50.
doi: 10.1007/BF00382637.

Disruption of spermatogenesis in Fasciola hepatica by some anthelmintics

B M Stammers
Comparative Study

Disruption of spermatogenesis in Fasciola hepatica by some anthelmintics

B M Stammers. Z Parasitenkd. .

Abstract

Eight-weeks old F. hepatica were recovered from rabbits and rats that had been treated with known fasciolicides and anthelmintics between 4 and 40 h previously. Examination of the surviving flukes showed that spermatogenesis was significantly disrupted by most of the fasciolicides but by none of the other anthelmintics. It is suggested that disruption of spermatogenesis is particularly associated with compounds showing activity against mature F. hepatica.

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