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. 2002 Feb;8(2):214-7.
doi: 10.3201/eid0802.010177.

Postexposure treatment and animal rabies, Ontario, 1958-2000

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Postexposure treatment and animal rabies, Ontario, 1958-2000

Christopher P Nunan et al. Emerg Infect Dis. 2002 Feb.

Abstract

This paper investigates the relationship between animal rabies and postexposure treatment (PET) in Ontario by examining the introduction of human diploid cell vaccine (HDCV) in 1980 and the initiation of an oral rabies vaccination program for wildlife in 1989. Introducing HDCV led to an immediate doubling of treatments. Both animal rabies and human treatments declined rapidly after the vaccination program was introduced, but human treatments have leveled off at approximately 1,000 per year.

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Figure
Figure
Postexposure treatment (PET) and laboratory-confirmed animal rabies. HCRV, human diploid cell vaccine; ORVP, oral rabies vaccination program; R2, coefficient of determination.

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References

    1. Ontario Ministry of Health. 59th annual report. Toronto: The Ministry; 1984.
    1. Noah DL, Smith MG, Gotthardt JC, Krebs JW, Green D, Childs JE. Mass human exposure to rabies in New Hampshire: exposures, treatment, and cost. Am J Public Health. 1996;86:1149–51. 10.2105/AJPH.86.8_Pt_1.1149 - DOI - PMC - PubMed
    1. Plotkin SA, Rupprecht CE, Koprowski H. Rabies vaccine. In: Plotkin SA, Orenstein WA, editors. Vaccines. 3rd ed. Philadelphia: WB Saunders Company; 1999. p. 743-66.
    1. Krebs JW, Long-Marin SC, Childs JE. Causes, costs and estimates of rabies postexposure prophylaxis treatments in the United States. J Public Health Manag Pract. 1998;4:56–62. - PubMed
    1. Moran GJ, Talan DA, Mower W, Newdow M, Ong S, Nakase JY, et al. Appropriateness of rabies postexposure prophylaxis treatment for animal exposures. JAMA. 2000;284:1001–7. 10.1001/jama.284.8.1001 - DOI - PubMed

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