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. 2002 Apr;46(4):1119-21.
doi: 10.1128/AAC.46.4.1119-1121.2002.

Activity of BMS-284756, a novel des-fluoro(6) quinolone, against Staphylococcus aureus, including contributions of mutations to quinolone resistance

D E Low  1 , M Muller, C L Duncan, B M Willey, J C de Azavedo, A McGeer, B N Kreiswirth, S Pong-Porter, D J Bast
Affiliations

Activity of BMS-284756, a novel des-fluoro(6) quinolone, against Staphylococcus aureus, including contributions of mutations to quinolone resistance

D E Low et al. Antimicrob Agents Chemother. 2002 Apr.

Abstract

The in vitro activity of BMS-284756 against 602 Staphylococcus aureus isolates, including 152 that were both methicillin and ciprofloxacin resistant (MIC > or = 4 microg/ml), was determined. For ciprofloxacin-susceptible and nonsusceptible isolates, the MICs at which 50% of organisms were inhibited were 0.015 and 2 microg/ml and the MICs at which 90% of organisms were inhibited were 0.03 and 4 microg/ml, respectively.

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Figures

FIG. 1.
FIG. 1.
Chemical structures of quinolone compounds.
See this image and copyright information in PMC

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