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. 1975 Oct;20(10):928-34.
doi: 10.1007/BF01070878.

Evaluation of endoscopic examination of colon tumors in rats

T Narisawa, C Q Wong, J H Weisburger

Evaluation of endoscopic examination of colon tumors in rats

T Narisawa et al. Am J Dig Dis. 1975 Oct.

Abstract

This study is an evaluation of the use of endoscopic examination to detect MNNG-induced large-bowel tumors in rats. The smallest human fiberbronchoscope was used as a colonoscope for the rats and the full length of the distal large bowel was visualized. The correct diagnosis rate in all rats with and without large-bowel tumors was 94%. Of rats with colon tumors, 85% were correctly diagnosed endoscopically. Even tumors 1 or 2 mm in diameter were detected. The examination was easy and reliable. This procedure may be an adjunct in experimental work with this and other animal models of colon cancer.

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References

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