Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
Review
. 2001 Dec;1(3):233-40.
doi: 10.1038/35106009.

Assessing TP53 status in human tumours to evaluate clinical outcome

T Soussi  1 , C Béroud
Affiliations
Review

Assessing TP53 status in human tumours to evaluate clinical outcome

T Soussi et al. Nat Rev Cancer. 2001 Dec.

Abstract

TP53 is probably the most extensively studied tumour-suppressor gene, and patients with TP53 mutations are known to have a poor outcome. However, inconsistencies in the analysis of TP53 status, and failure to realize that different mutations behave in different ways, prevent us from effectively applying our vast knowledge of this protein in clinical practice. What simple steps can be taken to ensure that patients benefit from our understanding of TP53?

PubMed Disclaimer

Publication types

MeSH terms

LinkOut - more resources